Developmental Toxicants: Mechanisms, Consequences, and Remediation - Core B: Analytical Chemistry Core

Status: 
Active
Investigators: 
P. Lee Ferguson (PI), Heather Stapleton (co-PI)
Funding Agency: 
NIEHS - Superfund Research Program

The Duke Superfund Research Center Analytical Core Facility enhances the biomedical and non-biomedical projects of this center by providing state-of-the-art analytical support to monitor and quantify organic contaminant levels, thus assisting in identification of mechanisms of developmental toxicity.  The ACC provides services for routine analyses of samples for organophosphate pesticides (e.g. chlorpyrifos), polycyclic aromatic hydrocarbons (PAHs), and brominated flame retardants (e.g. polybrominated diphenyl ethers). In addition this core facility conducts research to develop new methods for analysis of Superfund-relevant chemical contaminants and assists in the identification of contaminant degradation products and/or metabolites using high-resolution mass spectrometry.  This core also serves as a teaching and training center for Duke University undergraduate and graduate students.